Description

[1-(Isopropylideneamino)Butyl]Phosphonic Acid Bis(Trimethylsilyl) Ester is a specialized organophosphorus compound featuring a protected phosphonic acid group and an imine functionality. This unique structure makes it a valuable protected phosphonate building block and ligand precursor in advanced synthetic chemistry. It is primarily utilized by research institutions and chemical manufacturers engaged in the development of pharmaceuticals, agrochemicals, and novel materials, where precise control over phosphorus-containing intermediates is critical.

Application

• Pharmaceutical Intermediate: Serves as a key protected synthon in the synthesis of novel phosphonate-based drug candidates, including antiviral and bone-targeting therapeutics.
• Agrochemical Research: Used in the development of next-generation herbicides, plant growth regulators, and pesticides that utilize phosphonate chemistry.
• Ligand Synthesis: Acts as a precursor for the preparation of sophisticated nitrogen-phosphorus (N,P) ligands used in homogeneous catalysis and metal complexation.
• Material Science: Employed in the research of surface-modifying agents, flame retardants, and specialty polymers where phosphonate groups are incorporated.
• Organic Synthesis Building Block: Provides a versatile, silyl-protected phosphonate moiety for Horner-Wadsworth-Emmons and other carbon-carbon bond-forming reactions.

Basic Information

Product Name	[1-(Isopropylideneamino)Butyl]Phosphonic Acid Bis(Trimethylsilyl) Ester
CAS No.	55108-66-2
Molecular Formula	C13H32NO3PSi2
Molecular Weight	337.55 g/mol
Synonyms	Bis(trimethylsilyl) [1-(isopropylideneamino)butyl]phosphonate; (1-Isopropylideneaminobutyl)phosphonic Acid Bis(trimethylsilyl) Ester; Phosphonic Acid, [1-[(1-Methylethylidene)amino]butyl]-, Bis(trimethylsilyl) Ester; NSC 334044; (1-Isopropyliminobutyl)phosphonic Acid Bis(trimethylsilyl) Ester; TMS-Protected Butylphosphonate Imine; Silyl Ester of [1-(Isopropylideneamino)Butyl]Phosphonic Acid
EINECS	Contact for details

Quality Control

Our production of [1-(Isopropylideneamino)Butyl]Phosphonic Acid Bis(Trimethylsilyl) Ester adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is characterized by advanced analytical techniques including NMR, HPLC, and GC. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation upon prolonged exposure to air. Keep away from strong acids and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.