Description

Bofumustine CAS NO 55102-44-8 is a specialized nitrogen mustard alkylating agent, a key intermediate in advanced pharmaceutical synthesis. This compound is valued for its precise chemical reactivity, enabling the development of targeted therapeutic agents. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel oncology treatments and other specialized active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of complex nitrogen mustard-based chemotherapeutic agents and other specialized APIs.
• Oncology Research: Used in preclinical and clinical research for developing new alkylating antineoplastic drugs targeting various cancer cell lines.
• Biochemical Research: Employed in studies investigating DNA alkylation mechanisms and the development of targeted drug delivery systems.
• Process Development: Serves as a key starting material (KSM) or advanced intermediate in process chemistry for scale-up and optimization of drug manufacturing routes.

Basic Information

Product Name	Bofumustine
CAS No.	55102-44-8
Molecular Formula	C7H12Cl2N2O3
Molecular Weight	243.09 g/mol
Synonyms	1,3-Bis(2-chloroethyl)-1-nitrosourea (BCNU) Impurity; Carmustine related compound; NSC 409962; 1,3-Bis(2-chloroethyl)-1-nitrosourea; BCNU; Nitrumon; BiCNU; Gliadel
EINECS	Contact for details

Quality Control

Our Bofumustine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for pharmaceutical intermediates. Certificates of Analysis (COA) detailing purity (typically by HPLC), related substances, and other critical parameters are provided with every shipment to support your regulatory and research needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.