Description

2,3,5-Tri-o-Benzyl-D-Ribonolactone is a key protected intermediate in nucleoside and carbohydrate chemistry. This compound is essential for the controlled synthesis of complex bioactive molecules, offering a stable, benzyl-protected lactone framework for selective functionalization. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers for the production of antiviral agents, modified nucleosides, and other high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of nucleoside analogs and antiviral drugs.
• Carbohydrate Chemistry: Used for the preparation of protected ribose derivatives and complex oligosaccharides.
• Antiviral Agent Synthesis: Serves as a precursor in the manufacturing of active pharmaceutical ingredients (APIs) targeting viral infections.
• Fine Chemical Production: Employed in research and development for creating novel chemical entities and specialty compounds.
• Biochemical Research: Used as a standard or reagent in studies involving nucleic acid chemistry and enzyme mechanisms.
• Process Development: Acts as a starting material for scaling up the production of chiral, high-purity intermediates under GMP conditions.

Basic Information

Item	Detail
Product Name	2,3,5-Tri-o-Benzyl-D-Ribonolactone
CAS No.	55094-52-5
Molecular Formula	C26H26O5
Molecular Weight	418.48 g/mol
Synonyms	D-Ribono-1,4-lactone, 2,3,5-tris-O-(phenylmethyl)-; 2,3,5-Tri-O-benzyl-D-ribono-1,4-lactone; 2,3,5-Tris-O-benzyl-D-ribonolactone; Tri-O-benzyl-D-ribonolactone; NSC 334503; Benzyl-protected ribonolactone; D-Ribonolactone, 2,3,5-tribenzyl ether
EINECS	Contact for details

Quality Control

Our 2,3,5-Tri-o-Benzyl-D-Ribonolactone is produced under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and purity, chiral analysis, and identity confirmation. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support development and commercial projects requiring compliance with ICH guidelines and cGMP standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Optical Rotation	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.