Description

1-O,2-O,3-O,4-o-Tetrakis(trimethylsilyl)-6-deoxy-β-L-mannopyranose is a highly functionalized, silyl-protected carbohydrate derivative. This compound is a critical intermediate in synthetic organic chemistry, valued for its role in the stereoselective construction of complex sugar molecules and glycoconjugates. It is primarily utilized by research institutions and pharmaceutical companies engaged in carbohydrate chemistry, medicinal chemistry, and the development of novel therapeutics and diagnostics.

Application

• Glycosylation Intermediate: A key building block for the stereocontrolled synthesis of oligosaccharides, glycopeptides, and other complex glycostructures.
• Medicinal Chemistry Research: Used in the discovery and development of carbohydrate-based drugs, including antiviral, antibacterial, and anticancer agents.
• Chemical Biology Probes: Serves as a precursor for synthesizing labeled or modified sugars used to study biological recognition and metabolic pathways.
• Chiral Auxiliary/Synthon: Exploits its defined stereochemistry for the asymmetric synthesis of non-carbohydrate bioactive molecules.
• Process Chemistry: Employed in the scalable production of active pharmaceutical ingredients (APIs) where specific sugar motifs are required.
• Material Science: Potential use in creating functionalized surfaces or polymers with specific carbohydrate recognition properties.

Basic Information

Product Name	1-O,2-O,3-O,4-o-Tetrakis(trimethylsilyl)-6-deoxy-β-L-mannopyranose
CAS No.	55057-22-2
Molecular Formula	C22H52O5Si4
Molecular Weight	509.0 g/mol
Synonyms	6-Deoxy-β-L-mannopyranose, 1,2,3,4-tetrakis-O-(trimethylsilyl)-; Tetrakis-O-trimethylsilyl-6-deoxy-β-L-mannopyranose; β-L-6-Deoxymannose tetrakis(trimethylsilyl) ether; Per-O-trimethylsilylated 6-deoxy-β-L-mannose; TMS-protected 6-deoxy-β-L-mannose; 6-Deoxy-β-L-mannose TMS ether; 1,2,3,4-Tetra-O-trimethylsilyl-6-deoxy-β-L-mannopyranose
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We provide Certificates of Analysis (COA) for every batch, detailing purity and identity confirmation via advanced analytical techniques. Quality is assured through strict adherence to internal specifications, with testing typically including identification (NMR, IR), assay (HPLC), and impurity profiling. Certificates of Analysis (COA) are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation and moisture uptake. Store away from incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95% (Area %)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.