Description

(Z)-7-[(1R,2R,3R,5S)-5-Acetoxy-3-Hydroxy-2-((E)-(S)-3-Hydroxy-Oct-1-Enyl)-Cyclopentyl]-Hept-5-Enoic Acid Methyl Ester is a high-purity, synthetically produced prostaglandin analog, a critical intermediate in advanced pharmaceutical research and development. This compound is valued for its precise stereochemistry and functional groups, which are essential for biological activity studies and the synthesis of more complex therapeutic agents. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel treatments targeting inflammation, cardiovascular function, and reproductive health.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of prostaglandin-based drugs and other bioactive molecules.
• Biochemical Research: Used as a reference standard or active compound in studies of prostaglandin receptors, signal transduction pathways, and enzyme interactions.
• Drug Discovery & Development: Serves as a core scaffold for medicinal chemistry programs aimed at creating new anti-inflammatory, vasoactive, or cytoprotective agents.
• Academic Research: Employed in university and institutional labs for investigating the physiological roles and pharmacological modulation of eicosanoids.
• Process Chemistry: Used in the development and scale-up of synthetic routes for complex, stereospecific active pharmaceutical ingredients (APIs).

Basic Information

Product Name	(Z)-7-[(1R,2R,3R,5S)-5-Acetoxy-3-Hydroxy-2-((E)-(S)-3-Hydroxy-Oct-1-Enyl)-Cyclopentyl]-Hept-5-Enoic Acid Methyl Ester
CAS No.	55022-57-6
Molecular Formula	C23H38O6
Molecular Weight	410.55 g/mol
Synonyms	Methyl (5Z)-7-[(1R,2R,3R,5S)-5-(Acetyloxy)-3-hydroxy-2-[(1E,3S)-3-hydroxy-1-octen-1-yl]cyclopentyl]-5-heptenoate; 11-Deoxy-13,14-dihydro-16-phenoxy-PGE1 methyl ester (related analog); Prostaglandin E1 Methyl Ester Derivative; PGE1 Methyl Ester Analog; (Z)-7-[(1R,2R,3R,5S)-5-Acetoxy-3-hydroxy-2-[(1E,3S)-3-hydroxy-1-octenyl]cyclopentyl]-5-heptenoic acid methyl ester
EINECS	Contact for details

Quality Control

Our (Z)-7-[(1R,2R,3R,5S)-5-Acetoxy-3-Hydroxy-2-((E)-(S)-3-Hydroxy-Oct-1-Enyl)-Cyclopentyl]-Hept-5-Enoic Acid Methyl Ester is manufactured under strict quality systems. Each batch undergoes rigorous analytical testing, including chiral HPLC and NMR, to ensure high chemical and isomeric purity suitable for research and development applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation and degradation. Allow the container to reach room temperature in a desiccator before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Isomeric Purity (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.