Description

(5S,2R)-2,6,9α,10β-Tetramethyl-2-Vinyl-1-Oxaspiro[4.5]Dec-6-Ene is a high-purity, chiral spirocyclic compound with a complex molecular architecture, serving as a critical advanced intermediate in sophisticated organic syntheses. Its precise stereochemistry and unique oxaspiro[4.5]decene core make it an invaluable building block for constructing molecules with specific three-dimensional configurations. This compound is primarily sought after by research institutions and pharmaceutical development teams working on novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty fragrances.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of complex drug candidates, particularly for central nervous system (CNS) and anti-inflammatory targets.
• Agrochemical Research: Used in the development of novel pesticides and herbicides where specific stereochemistry is crucial for biological activity.
• Flavor & Fragrance Chemistry: Serves as a building block for creating unique, high-value odorants and flavoring agents with complex spirocyclic structures.
• Material Science Research: Investigated as a monomer or cross-linking agent for developing polymers with specialized thermal or optical properties.
• Academic & Process Chemistry: Employed in methodological studies for developing new asymmetric synthesis and spiroannulation reactions.
• Catalyst Ligand Synthesis: Potential precursor for synthesizing novel chiral ligands used in asymmetric catalysis.

Basic Information

Product Name	(5S,2R)-2,6,9α,10β-Tetramethyl-2-Vinyl-1-Oxaspiro[4.5]Dec-6-Ene
CAS No.	54990-55-5
Molecular Formula	C15H24O
Molecular Weight	220.35 g/mol
Synonyms	2-Vinyl-2,6,9α,10β-tetramethyl-1-oxaspiro[4.5]dec-6-ene; (2R,5S)-2-Ethenyl-2,6,9α,10β-tetramethyl-1-oxaspiro[4.5]dec-6-ene; 1-Oxaspiro[4.5]dec-6-ene, 2-ethenyl-2,6,9α,10β-tetramethyl-, (2R,5S)-; Spirocyclic vinyl ether intermediate; Chiral oxaspiro compound
EINECS	Contact for details

Quality Control

Our (5S,2R)-2,6,9α,10β-Tetramethyl-2-Vinyl-1-Oxaspiro[4.5]Dec-6-Ene is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure high chemical and stereochemical purity suitable for demanding research and development applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This compound may be sensitive to prolonged exposure to air and moisture; containers should be kept tightly sealed under an inert atmosphere when not in use.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.