Description

2-[(Trifluoroacetyl)Amino]Butanoic Acid 1-Methylpropyl Ester is a specialized fluorinated amino acid derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the trifluoroacetyl protecting group and ester functionality, which are essential for constructing complex molecules with precise stereochemistry and enhanced metabolic stability. This high-purity intermediate is primarily needed by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing novel active pharmaceutical ingredients (APIs), particularly peptidomimetics and protease inhibitors.

Application

• Pharmaceutical Intermediate: A key synthon in the multi-step synthesis of complex drug candidates, especially those targeting neurological and metabolic diseases.
• Peptidomimetic Research: Used to introduce non-natural, fluorinated amino acid residues into peptide backbones to enhance binding affinity and proteolytic resistance.
• Protease Inhibitor Development: Serves as a core scaffold or precursor for designing potent and selective enzyme inhibitors.
• Agrochemical Synthesis: Employed in creating advanced, fluorinated active ingredients for crop protection with improved efficacy and environmental profile.
• Material Science: Potential monomer or modifier for synthesizing specialty polymers with unique surface properties and chemical resistance.
• Chemical Biology Probes: Utilized in the design of activity-based probes and labeled compounds for studying biological pathways.

Basic Information

Product Name	2-[(Trifluoroacetyl)Amino]Butanoic Acid 1-Methylpropyl Ester
CAS No.	54986-68-4
Molecular Formula	C9H14F3NO3
Molecular Weight	241.21 g/mol
Synonyms	N-(Trifluoroacetyl)-D,L-norvaline sec-butyl ester; sec-Butyl 2-[(trifluoroacetyl)amino]butanoate; 2-[(Trifluoroacetyl)amino]butanoic acid sec-butyl ester; Norvaline, N-trifluoroacetyl-, sec-butyl ester; Butanoic acid, 2-[(trifluoroacetyl)amino]-, 1-methylpropyl ester; 1-Methylpropyl 2-[(trifluoroacetyl)amino]butanoate
EINECS	Contact for details

Quality Control

Our 2-[(Trifluoroacetyl)Amino]Butanoic Acid 1-Methylpropyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, GC for residual solvents, and NMR/IR for structural confirmation, to ensure it meets the exacting standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids, organic solvents, fluorides, and strong alkalis. The container must be kept tightly sealed in a dry environment to prevent moisture ingress.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.