Description

Butanoic Acid, 3-[(Trifluoroacetyl)Amino]-, 1-Methylpropyl Ester is a specialized organic compound featuring a trifluoroacetyl-protected amino acid ester structure. This molecular architecture makes it a valuable building block and intermediate in advanced synthetic chemistry, particularly for introducing chiral centers and fluorinated motifs. It is primarily utilized by pharmaceutical R&D and fine chemical synthesis sectors for the development of novel active ingredients and complex organic molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), especially those requiring fluorinated amino acid derivatives.
• Peptidomimetics Synthesis: Used in the construction of peptide analogs and mimetics where the trifluoroacetyl group provides specific steric and electronic properties.
• Agrochemical Research: Serves as a precursor in the synthesis of advanced, high-performance crop protection agents with potential enhanced activity or environmental profile.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for asymmetric catalysis and organometallic chemistry.
• Fluorine Chemistry Studies: Acts as a model compound in academic and industrial research focused on the incorporation and behavior of trifluoromethyl groups in organic molecules.
• Custom Synthesis Projects: A versatile starting material for contract research organizations (CROs) and CDMOs engaged in custom synthesis for clients in life sciences.

Basic Information

Product Name	Butanoic Acid, 3-[(Trifluoroacetyl)Amino]-, 1-Methylpropyl Ester
CAS No.	54986-67-3
Molecular Formula	C10H16F3NO3
Molecular Weight	255.24 g/mol
Synonyms	1-Methylpropyl 3-[(trifluoroacetyl)amino]butanoate; sec-Butyl 3-[(trifluoroacetyl)amino]butanoate; 3-(Trifluoroacetamido)butyric Acid sec-Butyl Ester; N-(Trifluoroacetyl)-D/L-3-Aminobutanoic Acid sec-Butyl Ester; (±)-sec-Butyl 3-[(trifluoroacetyl)amino]butyrate; TFAA-protected 3-Aminobutanoate sec-Butyl Ester
EINECS	Contact for details

Quality Control

Our Butanoic Acid, 3-[(Trifluoroacetyl)Amino]-, 1-Methylpropyl Ester is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and chiral purity analysis where applicable, to ensure identity, potency, and purity meet the stringent requirements of advanced synthetic applications. Certificates of Analysis (COA) detailing all specifications and test results are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. For long-term storage, consider holding under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.