Description

4-[(Trifluoroacetyl)Amino]Butanoic Acid (S)-1-Methylpropyl Ester is a specialized chiral intermediate of significant value in advanced synthetic chemistry. Its core value proposition lies in its unique trifluoroacetyl-protected amino acid ester structure, which is crucial for introducing specific functionalities and stereochemistry into target molecules. This compound is primarily needed by research and development laboratories and production facilities in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of complex drug candidates, particularly those requiring specific stereocenters and fluorinated motifs.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, where the trifluoromethyl group can enhance biological activity and metabolic stability.
• Peptide Mimetics & Prodrug Development: Serves as a protected amino acid derivative for constructing peptide analogs and designing prodrug strategies to improve pharmacokinetic properties.
• Ligand & Catalyst Preparation: Employed in the preparation of specialized chiral ligands and organocatalysts for asymmetric synthesis applications.
• Chemical Biology Research: Utilized as a molecular probe or a precursor for labeling reagents in proteomics and biochemical studies.
• Fine Chemical Production: Acts as a high-value intermediate in the custom synthesis of specialty chemicals for various industrial and research purposes.

Basic Information

Product Name	4-[(Trifluoroacetyl)Amino]Butanoic Acid (S)-1-Methylpropyl Ester
CAS No.	54986-66-2
Molecular Formula	C10H16F3NO3
Molecular Weight	255.24 g/mol
Synonyms	(S)-sec-Butyl 4-[(Trifluoroacetyl)Amino]Butanoate; (S)-1-Methylpropyl 4-[(Trifluoroacetyl)Amino]Butanoate; 4-(Trifluoroacetamido)Butanoic Acid (S)-sec-Butyl Ester; L-sec-Butyl 4-(Trifluoroacetamido)Butyrate; N-(Trifluoroacetyl)-4-aminobutanoic Acid (S)-1-Methylpropyl Ester; 4-(Trifluoroacetylamino)Butyric Acid (S)-sec-Butyl Ester; 54986-66-2; Butanoic acid, 4-[(trifluoroacetyl)amino]-, (1S)-1-methylpropyl ester
EINECS	Contact for details

Quality Control

Our 4-[(Trifluoroacetyl)Amino]Butanoic Acid (S)-1-Methylpropyl Ester is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis (HPLC, GC) and identity confirmation (NMR, IR), to ensure compliance with exacting research and pharmaceutical-grade standards. Comprehensive Certificates of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles are provided to guarantee batch-to-batch consistency and traceability for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This compound is sensitive to fluoride/strong alkali. Keep away from incompatible materials and sources of ignition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.