Description

[Ethyl(Trifluoroacetyl)Amino]Acetic Acid (S)-1-Methylpropyl Ester is a specialized chiral building block and intermediate of significant interest in advanced organic synthesis. Its core value lies in its trifluoroacetyl-protected amino acid ester structure, which is crucial for introducing specific functionalities and stereochemistry into target molecules. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and production of peptide mimetics and active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the development of advanced herbicides and pesticides requiring specific stereochemistry for efficacy.
• Chemical Research: Serves as a versatile building block in academic and industrial laboratories for exploring new synthetic methodologies.
• Peptide Chemistry: Employed in the synthesis of modified peptides and peptidomimetics, leveraging its protected amino acid ester functionality.
• Ligand and Catalyst Development: Acts as a precursor for creating chiral ligands and organocatalysts used in asymmetric synthesis.
• Fluorine Chemistry Studies: Provides a valuable template for studying the influence of the trifluoroacetyl group on chemical reactivity and biological activity.

Basic Information

Item	Details
Product Name	[Ethyl(Trifluoroacetyl)Amino]Acetic Acid (S)-1-Methylpropyl Ester
CAS No.	54986-51-5
Molecular Formula	C10H16F3NO3
Molecular Weight	255.24 g/mol
Synonyms	(S)-sec-Butyl N-(Ethoxycarbonyl)-N-(trifluoroacetyl)glycinate; (S)-1-Methylpropyl N-(Ethoxycarbonyl)-N-(trifluoroacetyl)glycinate; N-(Ethoxycarbonyl)-N-(trifluoroacetyl)glycine (S)-sec-Butyl Ester; N-Carbethoxy-N-trifluoroacetylglycine (S)-1-Methylpropyl Ester; Glycine, N-(ethoxycarbonyl)-N-(trifluoroacetyl)-, (S)-1-methylpropyl ester; (S)-sec-Butyl 2-((ethoxycarbonyl)(trifluoroacetyl)amino)acetate
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We employ advanced analytical techniques, including HPLC, GC, and NMR, to verify identity, purity, and chiral integrity. Certificates of Analysis (COA) detailing batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure containers are sealed tightly after use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.