Description

2-Methyl-3-[(Trifluoroacetyl)Amino]Propanoic Acid 1-Methylpropyl Ester is a specialized fluorinated organic building block with a unique trifluoroacetyl-protected amino acid ester structure. This compound is valued for its role as a key intermediate in the synthesis of complex molecules, particularly in pharmaceutical research and fine chemical manufacturing. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced material sectors for constructing novel compounds with enhanced properties.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of active pharmaceutical ingredients (APIs), especially those requiring fluorinated motifs for metabolic stability and bioavailability.
• Agrochemical Research: Used in developing novel pesticides and herbicides where the trifluoromethyl group can impart improved activity and environmental persistence.
• Peptidomimetics & Protease Inhibitors: Serves as a protected amino acid derivative in the design and synthesis of peptide analogs and enzyme inhibitors.
• Material Science: Potential monomer or precursor for specialty polymers and coatings with unique surface properties due to fluorine content.
• Chemical Biology Probes: Employed in the creation of labeled compounds and molecular probes for studying biological mechanisms.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthetic routes.

Basic Information

Product Name	2-Methyl-3-[(Trifluoroacetyl)Amino]Propanoic Acid 1-Methylpropyl Ester
CAS No.	54986-50-4
Molecular Formula	C10H16F3NO3
Molecular Weight	255.24 g/mol
Synonyms	1-Methylpropyl 2-Methyl-3-[(trifluoroacetyl)amino]propanoate; sec-Butyl 2-Methyl-3-(trifluoroacetamido)propionate; 3-(Trifluoroacetamido)-2-methylpropionic Acid sec-Butyl Ester; 2-Methyl-3-(trifluoroacetamido)propionic Acid 1-Methylpropyl Ester; N-(Trifluoroacetyl)-2-methyl-β-alanine sec-Butyl Ester; 54986-50-4; sec-Butyl 3-[(trifluoroacetyl)amino]-2-methylpropanoate
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for research and development. Each batch is analyzed using advanced techniques including HPLC, GC, NMR, and mass spectrometry to confirm identity, purity, and consistency. Certificates of Analysis (COA) are available upon request, providing full transparency on all critical parameters. We adhere to strict internal quality management protocols to ensure reliable supply for your critical synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.