Description

4-Cyclopropyl-4-Oxo-2-Butynoic Acid Ethyl Ester is a high-purity, specialized organic building block characterized by its unique cyclopropyl and alkyne ester functionalities. This compound is valued for its role as a versatile synthon in advanced pharmaceutical and agrochemical research, enabling the construction of complex molecular architectures. It is primarily sought by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and crop protection industries for synthesizing novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging the reactivity of the alkyne and ketone groups.
• Material Science Research: Serves as a precursor for specialty polymers and advanced organic materials requiring rigid, cyclopropyl-based backbones.
• Chemical Biology Probes: Employed in the creation of molecular probes and tags due to its "click chemistry"-compatible alkyne handle for bioconjugation.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic synthesis, including cycloaddition and cross-coupling reactions.

Basic Information

Product Name	4-Cyclopropyl-4-Oxo-2-Butynoic Acid Ethyl Ester
CAS No.	54966-48-2
Molecular Formula	C9H10O3
Molecular Weight	166.17 g/mol
Synonyms	Ethyl 4-cyclopropyl-4-oxobut-2-ynoate; 4-Cyclopropyl-4-oxo-2-butynoic acid ethyl ester; But-2-ynoic acid, 4-cyclopropyl-4-oxo-, ethyl ester; Ethyl 4-cyclopropyl-2-butynoate-4-one; 4-Oxo-4-cyclopropylbut-2-ynoic acid ethyl ester; Ethyl (4-cyclopropyl-4-oxo-2-butynoate); 2-Butynoic acid, 4-cyclopropyl-4-oxo-, ethyl ester
EINECS	Contact for details

Quality Control

Our 4-Cyclopropyl-4-Oxo-2-Butynoic Acid Ethyl Ester is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring GMP-grade intermediates and research materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The container should be kept tightly sealed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.