Description

3-Cyano-2-Fluoro-6-Picoline is a high-purity fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique molecular structure, featuring both cyano and fluoro substituents on the picoline backbone, makes it an invaluable precursor for creating complex, functionalized molecules. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: Key synthon for the research and development of new drug candidates, particularly in kinase inhibitor and other small molecule therapeutic programs.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the fluorine atom enhances biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized ligands used in homogeneous catalysis and material science applications.
• Functional Material Research: Employed in the creation of organic electronic materials, liquid crystals, and advanced polymers due to its electron-withdrawing characteristics.
• Chemical Research & Development: A versatile reagent in academic and industrial R&D labs for exploring novel fluorination and cyanation reactions.

Basic Information

Product Name	3-Cyano-2-Fluoro-6-Picoline
CAS No.	54957-80-1
Molecular Formula	C7H5FN2
Molecular Weight	136.13 g/mol
Synonyms	2-Fluoro-6-methyl-3-pyridinecarbonitrile; 2-Fluoro-3-cyano-6-methylpyridine; 6-Methyl-2-fluoro-3-cyanopyridine; 3-Cyano-2-fluoro-6-methylpyridine; 2-Fluoro-6-picoline-3-carbonitrile; 54957-80-1; 2-Fluoro-6-methylnicotinonitrile
EINECS	Contact for details

Quality Control

Every batch of 3-Cyano-2-Fluoro-6-Picoline is manufactured under a strict quality management system. We provide comprehensive analytical control to ensure batch-to-batch consistency and high purity, which is essential for sensitive synthetic applications. A detailed Certificate of Analysis (COA) confirming identity, purity, and impurity profiles via HPLC, GC, and NMR is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.