Description

Trifluoroacetic Acid Bicyclo[2.2.1]Heptan-2-Yl Ester is a specialized fluorinated organic ester derived from norbornane, offering unique steric and electronic properties due to its bicyclic framework and trifluoroacetyl group. This compound is valued for its role as a versatile building block and protecting group reagent in advanced synthetic chemistry, particularly where robust, acid-labile intermediates are required. It is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity, structurally complex intermediates.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the synthesis of complex drug candidates, especially those requiring the norbornane scaffold for conformational rigidity.
• Agrochemical Synthesis: Used in the development of novel pesticides and herbicides where the fluorinated ester group enhances biological activity and stability.
• Advanced Material Precursor: Acts as a monomer or modifying agent in the production of specialty polymers and coatings with tailored surface properties.
• Organic Synthesis Reagent: Functions as an effective protecting group for alcohols or as a trifluoroacetylating agent in multi-step synthetic routes.
• Catalysis & Ligand Development: Employed in the preparation of novel ligands and organocatalysts that leverage its unique steric profile.
• Fluorine Chemistry Research: A valuable compound for academic and industrial R&D focused on introducing fluorine atoms into complex molecular architectures.

Basic Information

Product Name	Trifluoroacetic Acid Bicyclo[2.2.1]Heptan-2-Yl Ester
CAS No.	54934-98-4
Molecular Formula	C9H9F3O2
Molecular Weight	206.16 g/mol
Synonyms	2-Norbornyl Trifluoroacetate; Bicyclo[2.2.1]heptan-2-yl Trifluoroacetate; endo/exo-2-Norbornanol Trifluoroacetate; 2-Trifluoroacetoxynorbornane; Norbornan-2-yl Trifluoroacetate; TFA Norbornyl Ester; 2-Norborneol Trifluoroacetate
EINECS	Contact for details

Quality Control

Our Trifluoroacetic Acid Bicyclo[2.2.1]Heptan-2-Yl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatography and spectroscopy, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment. We support cGMP compliance for pharmaceutical applications and can tailor quality protocols to meet specific customer requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its nature as a strong acid/organic solvent, it should be stored separately from bases, oxidizing agents, and incompatible materials. Containers should be kept tightly sealed when not in use to prevent moisture absorption and volatilization.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Isomeric Ratio (endo/exo)	Reported on COA

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.