Description

3,5-Dibromo-2-Fluoro-4-Hydroxypyridine is a halogenated pyridine derivative that serves as a versatile and critical building block in advanced organic synthesis. Its unique substitution pattern makes it a valuable precursor for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and agrochemicals. This high-purity intermediate is essential for research and production in pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific bromo, fluoro, and hydroxy functionalities into their target compounds.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, especially in medicinal chemistry programs targeting kinase inhibitors, antiviral agents, and other bioactive molecules.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and fungicides where the halogenated pyridine core contributes to biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis and coordination chemistry.
• Material Science Research: Employed in the synthesis of functionalized organic materials and molecular components for electronic or optical applications.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences market.

Basic Information

Product Name	3,5-Dibromo-2-Fluoro-4-Hydroxypyridine
CAS No.	54929-38-3
Molecular Formula	C5H2Br2FNO
Molecular Weight	274.88 g/mol
Synonyms	4-Hydroxy-3,5-dibromo-2-fluoropyridine; 2-Fluoro-3,5-dibromo-4-pyridinol; 3,5-Dibromo-2-fluoro-4(1H)-pyridinone; 2-Fluoro-3,5-dibromo-4-hydroxypyridine; 4-Pyridinol, 3,5-dibromo-2-fluoro-; DBFHP
EINECS	Contact for details

Quality Control

Every batch of 3,5-Dibromo-2-Fluoro-4-Hydroxypyridine is manufactured under a strict quality management system and undergoes comprehensive analytical testing. We provide material with typical purity grades of 97% to 99+% (HPLC) to meet diverse R&D and production needs. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is supplied with each shipment, ensuring full traceability and compliance with your internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture. Due to its chemical nature, it should be stored separately from strong bases and fluorides.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Typical 98-99%)
Melting Point	Contact for details
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.