Description

5-Chloro-2-Methoxynicotinic Acid is a high-purity, versatile nicotinic acid derivative serving as a critical building block in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs) and agrochemicals, where its specific substitution pattern enables precise molecular modifications. It is primarily needed by research institutions, pharmaceutical developers, and fine chemical manufacturers engaged in creating novel compounds for therapeutic and agricultural applications.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of complex drug molecules, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging its heterocyclic structure for biological activity.
• Chemical Research & Development: Serves as a versatile scaffold for medicinal chemistry, enabling the exploration of new chemical entities and structure-activity relationships (SAR).
• Fine Chemical Production: Employed in the multi-step synthesis of specialty chemicals, dyes, and other high-value organic compounds.
• Academic & Industrial Research: A valuable reagent for synthetic organic chemists in universities and corporate R&D labs for methodological studies and novel compound library generation.

Basic Information

Product Name	5-Chloro-2-Methoxynicotinic Acid
CAS No.	54916-65-3
Molecular Formula	C7H6ClNO3
Molecular Weight	187.58 g/mol
Synonyms	2-Methoxy-5-chloronicotinic Acid; 5-Chloro-2-methoxypyridine-3-carboxylic Acid; 3-Carboxy-5-chloro-2-methoxypyridine; 5-Chloro-2-methoxy-3-pyridinecarboxylic Acid; Nicotinic acid, 5-chloro-2-methoxy-; 54916-65-3 (CAS); 5-Chloro-2-methoxynicotinic acid
EINECS	Contact for details

Quality Control

Our 5-Chloro-2-Methoxynicotinic Acid is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and impurity profiling, to meet exacting customer specifications. Certificates of Analysis (COA) detailing all quality parameters are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong acids and incompatible materials. The product is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.