Description

2-[(Trimethylsilyl)Oxy]Hexanoic Acid Trimethylsilyl Ester is a specialized organosilicon compound featuring dual trimethylsilyl (TMS) protecting groups. This structure is highly valuable in synthetic organic chemistry, particularly for the protection of carboxylic acids and hydroxyl groups during multi-step synthesis. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity, moisture-sensitive intermediates for complex molecule construction.

Application

• Advanced Pharmaceutical Intermediates: Serves as a key protected intermediate in the synthesis of active pharmaceutical ingredients (APIs), especially where sensitive functional groups must be shielded from harsh reaction conditions.
• Agrochemical Synthesis: Used in the production of complex herbicide and pesticide molecules, leveraging its protective properties to control reactivity and improve yield.
• Peptide and Organic Synthesis: Acts as a versatile protecting group reagent for carboxylic acids in solid-phase and solution-phase peptide synthesis and other delicate organic transformations.
• Material Science Precursors: Employed in the development of silicon-containing polymers and advanced hybrid materials where controlled release of the acid functionality is required.
• Chemical Research & Development: A critical tool in academic and industrial R&D labs for method development and the synthesis of novel, complex organic structures.

Basic Information

Product Name	2-[(Trimethylsilyl)Oxy]Hexanoic Acid Trimethylsilyl Ester
CAS No.	54890-07-2
Molecular Formula	C12H28O3Si2
Molecular Weight	276.52 g/mol
Synonyms	Hexanoic acid, 2-(trimethylsilyl)oxy-, trimethylsilyl ester; Bis(trimethylsilyl) 2-(trimethylsilyloxy)hexanoate; 2-(Trimethylsiloxy)hexanoic acid trimethylsilyl ester; TMS-Protected 2-Hydroxyhexanoic Acid; 2-Hydroxyhexanoic Acid Bis(trimethylsilyl) Ether; 2-TMS-Oxy-hexanoic Acid TMS Ester; Contact for additional trade names and abbreviations.
EINECS	Contact for details

Quality Control

Every batch of 2-[(Trimethylsilyl)Oxy]Hexanoic Acid Trimethylsilyl Ester is produced and analyzed under strict quality management protocols to ensure consistency and high purity for demanding synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality systems are designed to support cGMP and ISO standards for traceability and reliability, making this product suitable for regulated research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.