Description

6-(4-Methylpiperazin-1-yl)nicotinonitrile is a high-value pharmaceutical intermediate and versatile chemical building block. This compound is crucial for its role in the synthesis of complex molecules, particularly in medicinal chemistry and drug discovery. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for developing new active ingredients.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other targeted therapies.
• Medicinal Chemistry Research: Used in high-throughput screening and combinatorial chemistry for lead compound optimization and structure-activity relationship (SAR) studies.
• Agrochemical Development: Serves as a precursor in the research and production of novel herbicides, fungicides, and plant growth regulators.
• Chemical Synthesis: A versatile nitrile-containing intermediate for further functionalization, including hydrolysis to amides or reduction to amines.
• Ligand and Catalyst Preparation: Used in the development of specialized ligands for metal catalysis and organocatalysts.

Basic Information

Product Name	6-(4-Methylpiperazin-1-yl)nicotinonitrile
CAS No.	54864-89-0
Molecular Formula	C11H13N5
Molecular Weight	215.26 g/mol
Synonyms	6-(4-Methyl-1-piperazinyl)-3-pyridinecarbonitrile; 3-Cyano-6-(4-methylpiperazin-1-yl)pyridine; 6-(4-Methylpiperazin-1-yl)nicotinonitrile; 2-(4-Methylpiperazin-1-yl)-5-cyanopyridine; 5-Cyano-2-(4-methyl-1-piperazinyl)pyridine; Nicotinonitrile, 6-(4-methyl-1-piperazinyl)-; 54864-89-0
EINECS	Contact for details

Quality Control

Every batch of 6-(4-Methylpiperazin-1-yl)nicotinonitrile is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.