Description

2-Amino-5-Chloronicotinaldehyde is a versatile and high-value pyridine derivative, serving as a critical building block in advanced organic synthesis. Its bifunctional nature, featuring both an amino and an aldehyde group on a chlorinated pyridine core, makes it indispensable for constructing complex heterocyclic scaffolds. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of various drug candidates, particularly those targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Synthesis: Used in the development of new-generation herbicides, fungicides, and insecticides with improved efficacy and selectivity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized chelating ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of functionalized polymers and organic electronic materials due to its electron-deficient aromatic system.
• Chemical Biology Probes: Utilized to create labeled compounds and molecular probes for studying biological pathways and enzyme functions.

Basic Information

Product Name	2-Amino-5-Chloronicotinaldehyde
CAS No.	54856-61-0
Molecular Formula	C6H5ClN2O
Molecular Weight	156.57 g/mol
Synonyms	5-Chloro-2-aminonicotinaldehyde; 2-Amino-5-chloropyridine-3-carboxaldehyde; 3-Formyl-5-chloro-2-aminopyridine; 5-Chloro-2-aminopyridine-3-carbaldehyde; 2-Amino-5-chloro-3-pyridinecarboxaldehyde; 5-Chloro-3-formyl-2-aminopyridine; 2-Amino-5-chloro-3-pyridylcarboxaldehyde; 5-Chloro-2-pyridinamine-3-carboxaldehyde
EINECS	Contact for details

Quality Control

Our 2-Amino-5-Chloronicotinaldehyde is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and commercial synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting key parameters such as assay, impurity profile, and physical characteristics.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.