Description

2,3-Dihydro-5-Phenyl-1H-2,4-Benzodiazepin-1-One is a high-purity benzodiazepine derivative, a key structural motif in medicinal chemistry. This compound is valued for its role as a versatile synthetic intermediate in the research and development of novel active pharmaceutical ingredients (APIs). It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of complex heterocyclic compounds. Its defined structure and purity are critical for ensuring reproducibility and efficacy in advanced chemical synthesis.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel benzodiazepine-based drug candidates targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to explore and optimize pharmacological properties of new chemical entities.
• Reference Standard: Serves as an analytical standard for quality control and method development in pharmaceutical analysis.
• Organic Synthesis: Employed as a specialized precursor for constructing complex fused-ring systems in academic and industrial research.
• Biochemical Tool Compound: Potential use in biochemical assays to study receptor-ligand interactions relevant to neurological pathways.

Basic Information

Product Name	2,3-Dihydro-5-Phenyl-1H-2,4-Benzodiazepin-1-One
CAS No.	54768-78-4
Molecular Formula	C₁₅H₁₂N₂O
Molecular Weight	236.27 g/mol
Synonyms	5-Phenyl-2,3-dihydro-1H-1,4-benzodiazepin-2-one; 5-Phenyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-2-one; 1H-2,4-Benzodiazepin-1-one, 2,3-dihydro-5-phenyl-; 5-Phenyl-2,3-dihydro-1H-1,4-benzodiazepin-2(3H)-one; NSC 163049; 5-Phenyl-1H-2,4-benzodiazepine-1-one, 2,3-dihydro-
EINECS	Contact for details

Quality Control

Our 2,3-Dihydro-5-Phenyl-1H-2,4-Benzodiazepin-1-One is manufactured under a strict quality management system. Each batch is subjected to comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.