Description

2-Methyl-2-(Trimethylsilylamino)Propionic Acid Trimethylsilyl Ester is a versatile organosilicon compound that serves as a key protected amino acid derivative and a valuable silylating agent in advanced organic synthesis. Its dual functionality makes it an essential building block for constructing complex molecules with precise stereochemistry and functional group compatibility. This high-purity intermediate is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of peptide mimetics, β-lactam antibiotics, and other active pharmaceutical ingredients (APIs) requiring protected amino acid functionalities.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and plant growth regulators where its silyl groups aid in introducing specific molecular motifs.
• Peptide Chemistry: Acts as a protected glycine analogue for solid-phase and solution-phase peptide synthesis, facilitating the incorporation of sterically hindered amino acids.
• Organometallic Catalyst Ligand: Employed in the preparation of specialized ligands for asymmetric catalysis, enhancing reaction selectivity and yield.
• Material Science Research: Serves as a precursor for silicon-containing polymers and hybrid organic-inorganic materials with tailored surface properties.
• Chemical Derivatization Agent: Utilized in analytical chemistry to silylate sensitive functional groups (e.g., -OH, -NH) in compounds for Gas Chromatography (GC) or Mass Spectrometry (MS) analysis.

Basic Information

Product Name	2-Methyl-2-(Trimethylsilylamino)Propionic Acid Trimethylsilyl Ester
CAS No.	54745-23-2
Molecular Formula	C10H25NO2Si2
Molecular Weight	247.49 g/mol
Synonyms	2-(Trimethylsilylamino)-2-methylpropionic Acid Trimethylsilyl Ester; 2-Methyl-2-[(trimethylsilyl)amino]propanoic Acid Trimethylsilyl Ester; N-(Trimethylsilyl)-2-methylalanine Trimethylsilyl Ester; N,O-Bis(trimethylsilyl)-2-methylalanine; 2-Methylalanine N,O-bis(trimethylsilyl) Derivative; TMS-Protected 2-Methylalanine; (Trimethylsilyl)aminoisobutyric Acid Trimethylsilyl Ester
EINECS	Contact for details

Quality Control

Our 2-Methyl-2-(Trimethylsilylamino)Propionic Acid Trimethylsilyl Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and synthesis applications. We employ advanced analytical techniques including GC, HPLC, and NMR to verify identity and purity. A comprehensive Certificate of Analysis (COA) detailing assay, impurity profile, and physical characteristics is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when opening the container to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.