Description

4-Bromo-1,8-Naphthyridine is a high-purity halogenated naphthyridine derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its unique bromine-substituted heterocyclic structure, which enables precise functionalization for creating complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries, particularly for developing active pharmaceutical ingredients (APIs), ligands, and functional organic materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in kinase inhibitor research and antiviral agents.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides, leveraging its heterocyclic core for bioactivity.
• Ligand & Catalyst Development: Serves as a precursor for nitrogen-containing ligands used in transition metal catalysis and coordination chemistry.
• Material Science Research: Employed in the synthesis of organic semiconductors, light-emitting diodes (OLEDs), and other functional organic electronic materials.
• Chemical Biology Probes: Utilized as a scaffold for developing molecular probes and diagnostic tools due to its modifiable bromine handle.
• Academic & R&D Laboratories: A fundamental reagent for methodological studies in cross-coupling reactions and heterocyclic chemistry.

Basic Information

Product Name	4-Bromo-1,8-Naphthyridine
CAS No.	54569-28-7
Molecular Formula	C8H5BrN2
Molecular Weight	209.04 g/mol
Synonyms	4-Bromo-1,8-naphthyridine; 1,8-Naphthyridine, 4-bromo-; 4-Bromonaphthyridine; 4-Bromo[1,8]naphthyridine; 4-Bromo-1,8-diazanaphthalene; Bromo-naphthyridine; 4-Br-1,8-Napy
EINECS	Contact for details

Quality Control

Our 4-Bromo-1,8-Naphthyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency suitable for demanding R&D and scale-up applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.