Description

7-Chloro-4-Hydroxy-[1,8]Naphthyridine-3-Carboxylic Acid is a high-purity, functionalized naphthyridine derivative serving as a critical building block in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel pharmaceutical agents, particularly in the research of antimicrobial and antiviral therapeutics. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of quinolone and naphthyridone-based antibiotics and other active pharmaceutical ingredients (APIs).
• Antimicrobial Research: Serves as a core scaffold for developing new compounds with potential antibacterial and antifungal activity.
• Chemical Synthesis Building Block: Used in organic synthesis for constructing complex heterocyclic systems due to its reactive carboxylic acid and chloro substituents.
• Agrochemical Development: Employed in research for creating new crop protection agents and pesticides.
• Biochemical Research: Utilized in studies targeting enzyme inhibition and as a ligand or probe in biochemical assays.
• Material Science: Potential intermediate for the synthesis of organic electronic materials or metal-organic frameworks (MOFs).

Basic Information

Product Name	7-Chloro-4-Hydroxy-[1,8]Naphthyridine-3-Carboxylic Acid
CAS No.	54563-42-7
Molecular Formula	C9H5ClN2O3
Molecular Weight	224.60 g/mol
Synonyms	7-Chloro-4-hydroxy-1,8-naphthyridine-3-carboxylic acid; 3-Carboxy-7-chloro-1,8-naphthyridin-4-ol; 7-Chloro-4-hydroxy[1,8]naphthyridine-3-carboxylic acid; 4-Hydroxy-7-chloro[1,8]naphthyridine-3-carboxylic acid; 7-Chloro-4-oxo-1,4-dihydro[1,8]naphthyridine-3-carboxylic acid; 7-Chloro-1,8-naphthyridine-3-carboxylic acid, 4-hydroxy-; 7-Chloro-4-hydroxy-1,8-naphthyridine-3-carboxylate
EINECS	Contact for details

Quality Control

Our 7-Chloro-4-Hydroxy-[1,8]Naphthyridine-3-Carboxylic Acid is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our production can adhere to cGMP standards for pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.