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Methyl 2-(Acetylamino)-4-O,6-o-(Methylboranediyl)-3-o-(Trimethylsilyl)-2-Deoxy-α-D-Glucopyranoside CAS NO 54477-01-9


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CAS No.:54477-01-9

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Methyl 2-(Acetylamino)-4-O,6-o-(Methylboranediyl)-3-o-(Trimethylsilyl)-2-Deoxy-α-D-Glucopyranoside is a sophisticated, multi-functional carbohydrate derivative featuring protective silyl and boranediyl groups. This compound is a critical advanced intermediate in synthetic organic chemistry, valued for its role in constructing complex glycomimetics and nucleoside analogs. It is primarily utilized by research institutions and pharmaceutical development teams working on novel therapeutics, diagnostic agents, and specialized chemical probes.

Application

  • Pharmaceutical Intermediate: Key building block for the synthesis of novel nucleoside-based antiviral or anticancer drug candidates.
  • Glycobiology Research: Used in the study of carbohydrate-protein interactions and the synthesis of complex oligosaccharides with specific protective group strategies.
  • Probe Development: Serves as a precursor for labeled sugars used in metabolic pathway tracing or imaging studies.
  • Medicinal Chemistry: Enables the exploration of structure-activity relationships (SAR) in sugar-modified bioactive molecules.
  • Process Chemistry: Employed in the development and scale-up of synthetic routes for high-value fine chemicals.
  • Academic Synthesis: A valuable reagent for methodology development and total synthesis projects in university and industrial R&D labs.

Basic Information

Product Name Methyl 2-(Acetylamino)-4-O,6-o-(Methylboranediyl)-3-o-(Trimethylsilyl)-2-Deoxy-α-D-Glucopyranoside
CAS No. 54477-01-9
Molecular Formula C15H30BNO6Si
Molecular Weight 359.30 g/mol
Synonyms Methyl 2-Acetamido-4,6-O-(methylboranediyl)-3-O-trimethylsilyl-2-deoxy-α-D-glucopyranoside; 2-Deoxy-2-acetamido-4,6-O-methylboranediyl-3-O-trimethylsilyl-α-D-glucopyranoside methyl glycoside; 1-O-Methyl-2-acetamido-4,6-O-methylboranediyl-3-O-trimethylsilyl-2-deoxy-α-D-glucopyranose; TMS-protected glucosamine boronate ester; α-Methyl glycoside of N-acetyl-3-O-TMS-4,6-O-methylboranediyl-D-glucosamine
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Quality Control

Every batch of Methyl 2-(Acetylamino)-4-O,6-o-(Methylboranediyl)-3-o-(Trimethylsilyl)-2-Deoxy-α-D-Glucopyranoside is produced and controlled under a strict quality management system. We employ advanced analytical techniques including NMR (¹H, ¹³C, ¹¹B), HPLC, and mass spectrometry to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when opening the container for use to prevent decomposition.

Specification

Item Specification
Appearance White to off-white solid
Identification (IR) Conforms to structure
Identification (NMR) Conforms to structure
Purity (HPLC) ≥ 95.0%
Water Content (KF) ≤ 1.0%
Residual Solvents (GC) Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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