Description

1-Ethoxy-3-Isocyanatopropane is a versatile isocyanate-functional compound used as a key building block in organic synthesis. This specialty chemical is valued for its reactivity, enabling the introduction of urethane and urea linkages into target molecules. It is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for developing novel polymers, coatings, and active ingredients.

Application

• Pharmaceutical Intermediates: Serves as a key synthon for introducing urethane or urea moieties in the development of active pharmaceutical ingredients (APIs) and prodrugs.
• Agrochemical Synthesis: Used in the manufacture of herbicides, fungicides, and pesticides, where its isocyanate group reacts with amines or alcohols to form bioactive compounds.
• Polymer & Resin Modification: Acts as a cross-linking agent or chain extender in the production of polyurethanes, polyureas, and specialty coatings, enhancing material properties like durability and chemical resistance.
• Surface Coating Agents: Employed in the formulation of high-performance industrial and automotive coatings to improve adhesion, hardness, and weatherability.
• Adhesive & Sealant Formulations: A reactive component in the synthesis of moisture-curing and heat-curing adhesives and sealants.
• Chemical Research & Development: A valuable reagent in academic and industrial R&D labs for exploring new organic reactions and material science applications.

Basic Information

Product Name	1-Ethoxy-3-Isocyanatopropane
CAS No.	54458-15-0
Molecular Formula	C6H11NO2
Molecular Weight	129.16 g/mol
Synonyms	3-Isocyanatopropyl ethyl ether; Ethyl 3-isocyanatopropyl ether; 1-Ethoxy-3-isocyanato-propane; 3-Isocyanato-1-ethoxypropane; NSC 163046; β-Isocyanatoethyl ethyl ether; Propane, 1-ethoxy-3-isocyanato-; Isocyanic acid, (3-ethoxypropyl) ester
EINECS	Contact for details

Quality Control

Our 1-Ethoxy-3-Isocyanatopropane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including assay and impurity profile determination by GC or HPLC, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee compliance with your research and production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at temperatures between 2°C and 8°C (refrigerated) to maximize stability. This product is hygroscopic (moisture-sensitive) and must be kept under a dry inert atmosphere (e.g., nitrogen or argon) to prevent degradation. Keep away from heat, sparks, open flames, and incompatible materials such as alcohols, amines, and strong bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.1%
Density (20°C)	~0.98 g/mL
Refractive Index (n20/D)	~1.425

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.