Description

(+/-)-Corey Lactone, 5-(4-Phenylbenzoate) is a key chiral synthon and advanced pharmaceutical intermediate. This compound is valued for its critical role in the stereoselective synthesis of complex bioactive molecules, particularly prostaglandins and their analogs. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and fine chemical sectors for developing novel therapeutic agents and conducting process chemistry.

Application

• Prostaglandin Synthesis: A pivotal building block for the stereocontrolled synthesis of prostaglandins (PGs) like PGE2, PGF2α, and their derivatives.
• Pharmaceutical Intermediate: Serves as a crucial advanced intermediate in the production of prostaglandin-based APIs for ophthalmology, gynecology, and gastroenterology.
• Asymmetric Synthesis: Employed in chiral pool synthesis and resolution processes to construct complex molecules with defined stereochemistry.
• Medicinal Chemistry Research: Used in R&D for designing and synthesizing novel drug candidates targeting inflammation, pain, and cardiovascular functions.
• Process Development: Applied in scaling up synthetic routes for prostaglandin analogs, optimizing yield and purity for commercial manufacturing.
• Fine Chemical Production: Utilized in the custom synthesis of high-value, specialty chemicals for advanced material science and agrochemical research.

Basic Information

Product Name	(+/-)-Corey Lactone, 5-(4-Phenylbenzoate)
CAS No.	54382-73-9
Molecular Formula	C24H26O4
Molecular Weight	378.47 g/mol
Synonyms	5-(4-Phenylbenzoyloxy)-2-cyclopenten-1-one; Corey Lactone Benzoate; 5-(4-Phenylbenzoyloxy)cyclopent-2-en-1-one; DL-Corey Lactone 5-(4-Phenylbenzoate); Prostaglandin F2α Lactone Intermediate; 2-Cyclopenten-1-one, 5-[(4-phenylbenzoyl)oxy]-; (±)-Corey Lactone 5-(4-Phenylbenzoate); 4-Phenylbenzoic Acid 5-Oxo-2-cyclopenten-1-yl Ester
EINECS	Contact for details

Quality Control

Our (+/-)-Corey Lactone, 5-(4-Phenylbenzoate) is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral analysis, to ensure it meets the stringent requirements for pharmaceutical intermediate applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and conformance to agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	Specified racemic mixture
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.