Description

L-Glutamic Benzyl Ester is a protected amino acid derivative widely used as a key chiral building block in organic synthesis. This compound is essential for the controlled introduction of glutamic acid into peptide chains and other complex molecules, enabling the production of high-value fine chemicals and pharmaceuticals. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, biotechnology, and agrochemical sectors for developing active ingredients and novel materials.

Application

• Peptide Synthesis: A crucial intermediate for the solid-phase and solution-phase synthesis of peptides and peptidomimetics, protecting the carboxylic acid side chain of glutamic acid.
• Pharmaceutical Intermediates: Serves as a key chiral synthon in the research and production of active pharmaceutical ingredients (APIs), particularly for neurological and metabolic drugs.
• Bioconjugation: Used in the preparation of modified peptides and protein conjugates for drug delivery systems and diagnostic probes.
• Agrochemical Research: Employed in the synthesis of novel amino acid-based fungicides and plant growth regulators.
• Academic & Industrial R&D: A fundamental reagent in medicinal chemistry and chemical biology research for exploring new therapeutic candidates.
• Fine Chemical Production: Acts as a building block for synthesizing specialty chemicals, flavors, and fragrances requiring specific stereochemistry.

Basic Information

Product Name	L-Glutamic Benzyl Ester
CAS No.	54322-10-0
Molecular Formula	C12H15NO4
Molecular Weight	237.25 g/mol
Synonyms	L-Glutamic Acid α-Benzyl Ester; H-Glu(OBzl)-OH; (S)-2-Amino-5-(benzyloxy)-5-oxopentanoic Acid; Benzyl L-Glutamate; Glutamic Acid Benzyl Ester; L-Glutamic Acid 1-Benzyl Ester; (S)-2-Aminopentanedioic Acid 5-Benzyl Ester; NSC 3349
EINECS	Contact for details

Quality Control

Our L-Glutamic Benzyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure high purity and consistency, meeting the stringent requirements for pharmaceutical and research applications. A Certificate of Analysis (COA) detailing purity, chiral purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% (L-Isomer)
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.