Description

1-o-Linoleoyl-2-O,3-o-Bis(Trimethylsilyl)Glycerol is a chemically modified glycerol derivative, specifically a silyl-protected linoleic acid ester. This compound is a critical synthetic intermediate and protecting group reagent, valued for its role in enabling complex organic syntheses, particularly in lipid and carbohydrate chemistry. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors who require high-purity building blocks for advanced R&D and production.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of complex drug molecules, prodrugs, and lipid-based active pharmaceutical ingredients (APIs).
• Lipid Research & Synthesis: Used as a protected glycerol derivative for the controlled synthesis of structured triglycerides, phospholipids, and other complex lipids.
• Chemical Protecting Group: The trimethylsilyl (TMS) groups act as protective moieties for hydroxyl functions during multi-step organic synthesis, allowing for selective reactions.
• Agrochemical Development: Employed in the research and production of advanced surfactants, adjuvants, and active ingredients that require specific lipid architectures.
• Specialty Polymer Synthesis: Functions as a monomer or modifier in creating polymers with tailored hydrophobic and release properties.
• Bioconjugation & Prodrug Strategies: Utilized in linking active molecules to lipid carriers or creating hydrolyzable prodrug forms to enhance bioavailability.

Basic Information

Product Name	1-o-Linoleoyl-2-O,3-o-Bis(Trimethylsilyl)Glycerol
CAS No.	54284-45-6
Molecular Formula	C30H60O4Si2
Molecular Weight	540.97 g/mol
Synonyms	1-Linoleoyl-2,3-bis-O-(trimethylsilyl)-sn-glycerol; 2,3-Bis-O-(trimethylsilyl)-1-linoleoylglycerol; Glycerol, 1-linoleoyl-2,3-bis-O-(trimethylsilyl)-; sn-Glycerol 1-linoleate 2,3-bis(trimethylsilyl) ether; TMS-protected linoleoyl glycerol; (2,3-Bis(trimethylsilyloxy)propyl) (9Z,12Z)-octadeca-9,12-dienoate
EINECS	Contact for details

Quality Control

Our 1-o-Linoleoyl-2-O,3-o-Bis(Trimethylsilyl)Glycerol is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chromatography (HPLC, GC) and spectroscopic methods (NMR, IR), to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed batch-specific results are provided to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions or inert atmosphere to prevent degradation. Keep away from strong acids and bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Purity (GC)	≥ 90.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.