Description

1,4-Dihydro-2,6-Dimethyl-4-(Pentafluorophenyl)-3,5-Pyridinedicarboxylic Acid Diethyl Ester is a high-purity, fluorinated dihydropyridine derivative that serves as a critical advanced intermediate in modern synthetic chemistry. Its unique structure, featuring a pentafluorophenyl group, makes it a valuable precursor for developing novel compounds with enhanced properties. This product is essential for researchers and manufacturers in the pharmaceutical and agrochemical sectors, particularly for synthesizing active ingredients and exploring new chemical entities.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel dihydropyridine-based drug candidates, including potential calcium channel blockers and other bioactive molecules.
• Agrochemical Research: Used in the development of new pesticides and herbicides, where the fluorinated aromatic ring can improve metabolic stability and biological activity.
• Material Science Precursor: Serves as a monomer or functional additive in the research of specialty polymers and advanced materials requiring fluorinated components.
• Organic Synthesis Reagent: Employed in academic and industrial R&D for constructing complex heterocyclic frameworks and introducing pentafluorophenyl substituents.
• Fluorine Chemistry Studies: An important compound for investigating structure-activity relationships (SAR) and the effects of perfluoroaromatic substitution in molecular design.

Basic Information

Product Name	1,4-Dihydro-2,6-Dimethyl-4-(Pentafluorophenyl)-3,5-Pyridinedicarboxylic Acid Diethyl Ester
CAS No.	54280-71-6
Molecular Formula	C19H18F5NO4
Molecular Weight	419.35 g/mol
Synonyms	4-(Pentafluorophenyl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylic acid diethyl ester; Diethyl 4-(pentafluorophenyl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate; Pentafluorophenyl DHP Ester; 1,4-DHP-4-PFP Diethyl Ester; Felodipine Impurity; Felodipine Related Compound; 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(pentafluorophenyl)-, diethyl ester
EINECS	Contact for details

Quality Control

Our 1,4-Dihydro-2,6-Dimethyl-4-(Pentafluorophenyl)-3,5-Pyridinedicarboxylic Acid Diethyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) detailing purity, impurities, and full characterization data are provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the product under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, open flames, and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.