Description

2-Hydrazinyl-3-Iodopyridine is a versatile and highly functionalized heterocyclic building block, primarily valued for its dual reactive sites—the hydrazinyl and iodo groups—which enable sophisticated cross-coupling and cyclization reactions. This compound is essential for researchers and process chemists developing novel active pharmaceutical ingredients (APIs), agrochemicals, and advanced materials. Its primary demand comes from the pharmaceutical and agrochemical R&D sectors, where it serves as a key intermediate in synthesizing complex molecules with potential biological activity.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly in creating fused pyridine and pyrazolo[3,4-b]pyridine scaffolds for kinase inhibitors and other therapeutic agents.
• Agrochemical Synthesis: Used in the development of new-generation herbicides, fungicides, and insecticides, leveraging its structure to build compounds with specific modes of action.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing specialized nitrogen-containing ligands used in transition metal catalysis.
• Material Science Research: Employed in the creation of organic electronic materials and metal-organic frameworks (MOFs) due to its ability to form complex chelates.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and tags for studying biological processes and target engagement.

Basic Information

Item	Detail
Product Name	2-Hydrazinyl-3-Iodopyridine
CAS No.	54231-42-4
Molecular Formula	C5H6IN3
Molecular Weight	235.02 g/mol
Synonyms	3-Iodo-2-hydrazinylpyridine; 2-Hydrazino-3-iodopyridine; 3-Iodopyridin-2-ylhydrazine; 2-Hydrazinyl-3-iodopyridine; (3-Iodopyridin-2-yl)hydrazine; 54231-42-4; 3-Iodo-2-pyridinylhydrazine
EINECS	Contact for details

Quality Control

Our 2-Hydrazinyl-3-Iodopyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and development. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to handle and store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term stability, especially after opening the original packaging.

Specification

Item	Specification
Appearance	White to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.