Description

4-(Bromomethyl)Pyrimidine CAS NO 54198-78-6 is a versatile brominated pyrimidine derivative that serves as a crucial alkylating agent and building block in advanced organic synthesis. Its reactive bromomethyl group makes it an essential intermediate for constructing complex molecular architectures, particularly in pharmaceutical and agrochemical research. This high-purity compound is primarily sought by R&D chemists and process development scientists in the life sciences and fine chemical industries.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), especially kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and plant growth regulators.
• Ligand & Catalyst Development: Serves as a precursor for pyrimidine-based ligands used in transition metal catalysis and material science.
• Chemical Biology & Proteomics: Employed in the design of molecular probes, affinity tags, and activity-based protein profiling (ABPP) reagents.
• Material Science: Intermediate for creating functionalized polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: A valuable substrate in Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to introduce the pyrimidine moiety.

Basic Information

Product Name	4-(Bromomethyl)Pyrimidine
CAS No.	54198-78-6
Molecular Formula	C5H5BrN2
Molecular Weight	173.01 g/mol
Synonyms	4-(Bromomethyl)pyrimidine; Pyrimidine, 4-(bromomethyl)-; 4-Pyrimidinemethanol, 1-bromo-; 1-Bromo-4-pyrimidinemethanol; (Bromomethyl)pyrimidine; 4-Bromomethylpyrimidine; 4-Pyrimidinylmethyl bromide
EINECS	Contact for details

Quality Control

Our 4-(Bromomethyl)Pyrimidine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring GMP-grade intermediates and research chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber glass or opaque.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.