Description

Methanesulfinic Acid Trimethylsilyl Ester is a versatile organosilicon reagent primarily used as a protected form of methanesulfinic acid. This compound is crucial for synthetic chemists as it provides a stable, moisture-sensitive handle for introducing the methanesulfinyl group into target molecules under controlled conditions. It is an essential building block in pharmaceutical research, agrochemical development, and advanced material science for constructing complex sulfoxide and sulfone derivatives.

Application

• Pharmaceutical Intermediate: Key reagent in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing sulfoxide moieties.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where the sulfinyl group is a critical functional element.
• Organic Synthesis Reagent: Acts as a protected sulfinic acid equivalent in palladium-catalyzed cross-coupling reactions and nucleophilic additions.
• Material Science Precursor: Employed in the surface modification of materials and the creation of specialized polymers with sulfur-containing side chains.
• Chemical Research & Development: A valuable tool for methodology development in academic and industrial R&D laboratories exploring new sulfuration reactions.

Basic Information

Item	Details
Product Name	Methanesulfinic Acid Trimethylsilyl Ester
CAS No.	54193-90-7
Molecular Formula	C4H12O2SSi
Molecular Weight	152.29 g/mol
Synonyms	Trimethylsilyl methanesulfinate; Methanesulfinic Acid TMS Ester; Trimethylsilyl Methanesulfinate; TMS Methanesulfinate; Silyl Ester of Methanesulfinic Acid; Methylsulfinyloxytrimethylsilane; (Trimethylsilyl)methylsulfinate
EINECS	Contact for details

Quality Control

Our production of Methanesulfinic Acid Trimethylsilyl Ester adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including GC, NMR, and Karl Fischer titration, to ensure high chemical purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment. We support compliance with global regulatory frameworks, including REACH.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.