Description

5-Chloro-6-Hydroxynicotinic Acid is a versatile and high-purity organic building block, essential for advanced chemical synthesis. Its core value lies in its functionalized pyridine structure, which serves as a critical intermediate for developing complex molecules with targeted biological or material properties. This compound is primarily needed by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting neurological or metabolic pathways.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Development: Serves as a starting material for creating complex chelating ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the development of functionalized polymers, metal-organic frameworks (MOFs), and advanced organic electronic materials.
• Chemical Biology Probes: Utilized to create molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis and Contract Manufacturing: A fundamental building block for custom chemical synthesis services catering to R&D and scale-up projects.

Basic Information

Product Name	5-Chloro-6-Hydroxynicotinic Acid
CAS No.	54127-63-8
Molecular Formula	C6H4ClNO3
Molecular Weight	173.55 g/mol
Synonyms	6-Hydroxy-5-chloronicotinic Acid; 5-Chloro-6-hydroxy-3-pyridinecarboxylic Acid; 3-Pyridinecarboxylic acid, 5-chloro-6-hydroxy-; 5-Chloro-6-hydroxynicotinic acid; 5-Chloro-6-hydroxy-pyridine-3-carboxylic acid
EINECS	Contact for details

Quality Control

Our 5-Chloro-6-Hydroxynicotinic Acid is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) documenting all critical parameters are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.