Description

2,3-Dichloropyridine-5-Carbonyl Chloride is a highly reactive and versatile chemical building block, primarily used as a key intermediate in advanced organic synthesis. Its value lies in its dual functionality, enabling the construction of complex heterocyclic compounds and active pharmaceutical ingredients (APIs). This compound is essential for research and development chemists, process engineers, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel molecules.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of complex drug molecules, particularly those containing functionalized pyridine cores for antiviral, anticancer, or central nervous system (CNS) agents.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides where the dichloropyridine moiety imparts specific biological activity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in metal-catalyzed cross-coupling reactions and other catalytic processes.
• Material Science Research: Employed in the development of organic electronic materials, such as electron-transport layers or components for OLEDs, due to its electron-deficient aromatic system.
• Custom Synthesis and Contract Manufacturing: A valuable reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for client projects.

Basic Information

Product Name	2,3-Dichloropyridine-5-Carbonyl Chloride
CAS No.	54127-29-6
Molecular Formula	C7H2Cl3NO
Molecular Weight	230.46 g/mol
Synonyms	5-(Chlorocarbonyl)-2,3-dichloropyridine; 2,3-Dichloropyridine-5-carboxylic acid chloride; 2,3-Dichloro-5-pyridinecarbonyl chloride; 2,3-Dichloropyridine-5-carbonyl chloride; 5-Carboxy-2,3-dichloropyridine chloride; 2,3-Dichloro-5-(chloroformyl)pyridine; 2,3-Dichloropyridine-5-carboxyl chloride
EINECS	Contact for details

Quality Control

Our production of 2,3-Dichloropyridine-5-Carbonyl Chloride adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including HPLC, GC, and NMR to verify identity and quantify impurities. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment, ensuring full traceability and compliance with your internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent hydrolysis. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.