Description

Ethyl 4-Hydroxy-3,5-Diiodobenzoate is a high-purity iodinated aromatic ester compound, serving as a critical synthetic intermediate and building block in advanced organic synthesis. Its value lies in the strategic placement of iodine atoms and the ethyl ester group, which facilitate further functionalization for creating complex molecular architectures. This product is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require precise, high-quality intermediates for developing active ingredients and novel materials.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of thyroid hormone analogs, X-ray contrast media agents, and other iodinated active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the research and development of novel herbicides and fungicides where the diiodophenol moiety provides specific biological activity.
• Liquid Crystal & OLED Materials: Serves as a precursor for iodinated derivatives used in the production of advanced electronic display materials and organic light-emitting diodes.
• Polymer Modification: Acts as a functional monomer or cross-linking agent for introducing aromatic and halogenated units into polymer chains to alter physical properties.
• Chemical Research & Development: A versatile reagent for Suzuki-Miyaura and other palladium-catalyzed cross-coupling reactions due to the reactivity of the aryl iodide bonds.
• Dye & Pigment Manufacturing: Intermediate in the synthesis of specialized iodinated dyes and pigments for niche industrial applications.

Basic Information

Item	Detail
Product Name	Ethyl 4-Hydroxy-3,5-Diiodobenzoate
CAS No.	54073-94-8
Molecular Formula	C9H8I2O3
Molecular Weight	417.97 g/mol
Synonyms	Benzoic acid, 4-hydroxy-3,5-diiodo-, ethyl ester; Ethyl 3,5-diiodo-4-hydroxybenzoate; 4-Hydroxy-3,5-diiodobenzoic acid ethyl ester; Ethyl 4-hydroxy-3,5-diiodobenzoate; 3,5-Diiodo-4-hydroxybenzoic acid ethyl ester; Ethyl 3,5-diiodosalicylate (common name variant); EHDIB (abbreviation)
EINECS	Contact for details

Quality Control

Our Ethyl 4-Hydroxy-3,5-Diiodobenzoate is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure high purity and consistent performance. Standard quality parameters include assay (HPLC), identification (IR, NMR), and control of related substances. Certificates of Analysis (COA) detailing all test results are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, prolonged exposure to light should be avoided to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	158°C - 162°C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.