Description

5,6-Dihydro-4-Methyl-1-Phenyl-4H-[1,2,4]Triazolo[4,3-A][1,5]Benzodiazepine is a high-purity pharmaceutical intermediate belonging to the benzodiazepine class of heterocyclic compounds. Its value lies in its role as a key synthetic building block for the research and development of novel active pharmaceutical ingredients (APIs). This compound is primarily needed by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of specialized therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of novel benzodiazepine-derived therapeutic compounds.
• Medicinal Chemistry Research: Used as a scaffold or starting material for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and impurity profiling.
• Academic Research: Utilized in universities and research institutes for studying heterocyclic chemistry, reaction mechanisms, and new synthetic methodologies.
• Custom Synthesis: A starting point for contract research organizations (CROs) and CDMOs producing custom APIs and advanced intermediates for clients.

Basic Information

Product Name	5,6-Dihydro-4-Methyl-1-Phenyl-4H-[1,2,4]Triazolo[4,3-A][1,5]Benzodiazepine
CAS No.	54028-91-0
Molecular Formula	C18H16N4
Molecular Weight	288.35 g/mol
Synonyms	4-Methyl-1-phenyl-4H-[1,2,4]triazolo[4,3-a][1,5]benzodiazepine; 5,6-Dihydro-4-methyl-1-phenyl-4H-[1,2,4]triazolo[4,3-a][1,5]benzodiazepine; 1-Phenyl-4-methyl-4H-[1,2,4]triazolo[4,3-a][1,5]benzodiazepine; NSC 339579; Triazolobenzodiazepine Derivative; Benzodiazepine Triazole Fused Intermediate
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the exacting standards required for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep the container sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.