Description

Phenylalanine, α-Ethyl-β-Oxo-, Methyl Ester is a specialized chiral building block and synthetic intermediate of significant interest in advanced organic synthesis. Its unique structure, featuring both ester and keto functionalities on a phenylalanine-derived backbone, makes it a valuable precursor for constructing complex molecules. This compound is primarily sought after by research institutions and pharmaceutical development teams working on novel active pharmaceutical ingredients (APIs), peptide mimetics, and other fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new therapeutic agents, particularly for central nervous system (CNS) targets.
• Peptidomimetics Research: Serves as a non-natural amino acid derivative for designing and synthesizing peptide analogs with enhanced stability or biological activity.
• Asymmetric Synthesis: Used as a starting material or intermediate in catalytic asymmetric reactions to introduce chiral centers into complex molecular architectures.
• Chemical Biology Probes: Employed in the synthesis of labeled compounds or molecular probes for studying biological pathways and enzyme mechanisms.
• Academic & Industrial R&D: Fundamental research in organic chemistry methodologies and process development for scale-up synthesis.

Basic Information

Product Name	Phenylalanine, α-Ethyl-β-Oxo-, Methyl Ester
CAS No.	54011-38-0
Molecular Formula	C₁₄H₁₇NO₃
Molecular Weight	247.29 g/mol
Synonyms	Methyl 2-ethyl-3-oxo-3-phenylpropanoate; 2-Ethyl-3-oxo-3-phenylpropionic acid methyl ester; α-Ethyl-β-oxo-benzenepropanoic acid methyl ester; (RS)-2-Ethyl-3-oxo-3-phenylpropionic acid methyl ester; Methyl α-ethyl-β-oxo-hydrocinnamate; DL-2-Ethyl-3-oxo-3-phenylpropionic acid methyl ester; Phenylalanine derivative, α-ethyl-β-oxo methyl ester
EINECS	Contact for details

Quality Control

Our Phenylalanine, α-Ethyl-β-Oxo-, Methyl Ester is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and a Certificate of Analysis (COA) with key parameters including assay, chiral purity (if applicable), and impurity profile. Specifications can be aligned with research-grade or GMP-grade requirements based on customer needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). The product may be hygroscopic; keep the container tightly sealed to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Chiral Purity (if applicable)	Contact for details
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.