Description

5-Bromo-2-Chloropyridine is a versatile and high-purity halogenated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its value lies in providing a reactive scaffold for constructing complex molecules, particularly in the pharmaceutical and agrochemical sectors. This intermediate is essential for researchers and manufacturers in fine chemical, pharmaceutical R&D, and material science industries seeking reliable, high-quality raw materials for their processes.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, leveraging its halogenated structure for bioactivity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and coordination chemistry.
• Material Science Research: Employed in the synthesis of functionalized polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and Negishi cross-coupling reactions to form biaryl and other complex structures.
• Nucleophilic Aromatic Substitution: The halogen atoms provide sites for selective substitution, enabling the introduction of various functional groups.

Basic Information

Product Name	5-Bromo-2-Chloropyridine
CAS No.	53939-30-3
Molecular Formula	C5H3BrClN
Molecular Weight	192.44 g/mol
Synonyms	2-Chloro-5-bromopyridine; 5-Bromo-2-chloropyridine; 2-Chloro-5-bromo-pyridine; 5-Bromo-2-chloro-pyridine; Pyridine, 5-bromo-2-chloro-; 53939-30-3; NSC 404087
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-Chloropyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We are committed to meeting the stringent requirements of cGMP and ISO standards for our pharmaceutical-grade customers.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive and should be stored away from direct light exposure.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Purity (GC)	≥97.0%
Melting Point	64 - 68 °C
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.