Description

(Acetylamino)(3-Oxopropyl)Malonic Acid Diethyl Ester is a specialized malonic acid derivative that serves as a versatile and high-value synthetic intermediate. Its molecular structure, featuring both acetylamino and oxopropyl functionalities, makes it a critical building block for constructing complex heterocyclic and pharmaceutical scaffolds. This compound is essential for R&D and production chemists in the pharmaceutical, agrochemical, and advanced material sectors seeking to develop novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of complex drug molecules, particularly those containing nitrogen heterocycles and β-keto ester motifs.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and plant growth regulators requiring specific malonate-based structures.
• Organic Synthesis Building Block: Employed in multi-step synthetic routes for constructing complex natural product analogs and specialty chemicals.
• Research & Development: A valuable reagent in academic and industrial R&D labs for exploring new chemical reactions and developing novel compound libraries.
• Fine Chemical Production: Intermediate in the manufacture of dyes, pigments, and performance chemicals where precise molecular architecture is required.

Basic Information

Product Name	(Acetylamino)(3-Oxopropyl)Malonic Acid Diethyl Ester
CAS No.	53908-65-9
Molecular Formula	C12H19NO6
Molecular Weight	273.28 g/mol
Synonyms	Diethyl (Acetylamino)(3-Oxopropyl)malonate; 3-(Diethoxycarbonyl)(acetylamino)propanoic Acid; 2-(Acetylamino)-2-(3-oxopropyl)malonic Acid Diethyl Ester; Acetamide, N-[2,2-bis(ethoxycarbonyl)-4-oxobutyl]-; N-[2,2-Bis(ethoxycarbonyl)-4-oxobutyl]acetamide; Malonic acid, (acetylamino)(3-oxopropyl)-, diethyl ester; Acetylaminomalonic acid diethyl ester oxopropyl derivative
EINECS	Contact for details

Quality Control

Our (Acetylamino)(3-Oxopropyl)Malonic Acid Diethyl Ester is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring high-purity intermediates under cGMP or ISO 9001 frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to the potential for ester hydrolysis and ketone reactivity, the container should be kept tightly sealed under an inert atmosphere if long-term storage is required.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.