Description

(1R,7Ar)-Octahydro-1-[(S)-1-Isocyano-2-Methylpropyl]-3Aα-Methyl-7-Methylene-1H-Indene is a specialized chiral isocyanide building block of significant interest in advanced organic synthesis. Its value lies in its rigid, functionalized bicyclic structure, which serves as a key precursor for constructing complex molecular architectures. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for applications in medicinal chemistry, catalysis, and the synthesis of novel bioactive compounds.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of complex drug candidates and natural product analogs.
• Ligand & Catalyst Development: Used in the preparation of novel isocyanide-based ligands for transition metal catalysis and organocatalysis.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and library synthesis for high-throughput screening.
• Agrochemical Synthesis: Serves as a building block for developing new active ingredients with specific stereochemistry.
• Material Science Precursor: Potential use in the synthesis of functional polymers and advanced materials with tailored properties.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic synthesis and asymmetric reactions.

Basic Information

Item	Detail
Product Name	(1R,7Ar)-Octahydro-1-[(S)-1-Isocyano-2-Methylpropyl]-3Aα-Methyl-7-Methylene-1H-Indene
CAS No.	53822-96-1
Molecular Formula	C16H25N
Molecular Weight	231.38 g/mol
Synonyms	(1R,7aR)-1-[(1S)-1-Isocyano-2-methylpropyl]octahydro-3a-methyl-7-methylene-1H-indene; (1R,7aR)-1-[(S)-1-Isocyano-2-methylpropyl]octahydro-3a-methyl-7-methylene-1H-indene; (+)-α-Isocyano-3-Carene; 3-Carene Isocyanide Derivative; Chiral Isocyanoterpene; Terpene-Based Isocyanide; (1S,3aR,7aR)-1-Isocyano-2-methylpropyl-3a-methyl-7-methylidene-octahydro-1H-indene
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch is characterized using advanced analytical techniques to confirm identity, purity, and chiral integrity. Certificates of Analysis (COA) are available upon request, detailing specifications such as assay, enantiomeric excess, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its light-sensitive nature, containers should be kept in opaque or amber glass under an inert atmosphere for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.