Description

3-Pyridinecarbonyl Chloride, 2-Methoxy- (9Ci) is a versatile and reactive heterocyclic acid chloride derivative, serving as a critical building block in advanced organic synthesis. Its core value lies in its ability to introduce the 2-methoxypyridine-3-carbonyl moiety, a key structural motif for modulating biological activity and material properties. This high-purity intermediate is essential for researchers and process chemists in the pharmaceutical, agrochemical, and specialty chemical industries developing novel active ingredients and functional materials. The compound is supplied with a Certificate of Analysis to ensure batch-to-batch consistency and reliability for your sensitive synthetic applications.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and central nervous system (CNS) drug discovery programs.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides where the 2-methoxypyridine scaffold contributes to efficacy and selectivity.
• Ligand and Catalyst Development: Serves as a precursor for creating novel ligands in coordination chemistry and catalysts for asymmetric synthesis.
• Material Science Research: Employed in the synthesis of functional polymers, liquid crystals, and organic electronic materials requiring specific heterocyclic units.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.
• Chemical Biology & Proteomics: Can be used to create affinity probes, enzyme inhibitors, or labeling reagents for studying biological systems.

Basic Information

Product Name	3-Pyridinecarbonyl Chloride, 2-Methoxy- (9Ci)
CAS No.	53750-65-5
Molecular Formula	C7H6ClNO2
Molecular Weight	171.58 g/mol
Synonyms	2-Methoxynicotinoyl Chloride; 2-Methoxypyridine-3-carbonyl Chloride; 3-Carboxy-2-methoxypyridine Chloride; 2-Methoxy-3-pyridinecarboxylic Acid Chloride; 2-Methoxy-3-pyridinylcarbonyl Chloride; 2-Methoxynicotinic Acid Chloride; 2-Methoxy-3-pyridinecarbonyl Chloride
EINECS	Contact for details

Quality Control

Every batch of 3-Pyridinecarbonyl Chloride, 2-Methoxy- (9Ci) is manufactured and tested under a strict quality management system. We employ advanced analytical techniques including HPLC, GC, NMR, and IR spectroscopy to ensure identity, purity, and consistency meet the high standards required for synthetic applications. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment. Our quality commitment aligns with cGMP principles where applicable, ensuring a reliable supply for critical research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent hydrolysis. Keep away from strong bases, oxidizing agents, and sources of ignition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.