Description

Tripiperaquine is a synthetic antimalarial compound belonging to the bisquinoline class. Its primary commercial value lies in its potent activity against drug-resistant strains of *Plasmodium falciparum*, making it a critical component in modern combination therapies. This product is essential for pharmaceutical manufacturers and research institutions focused on developing and producing advanced antimalarial medications and conducting parasitology research.

Application

• Pharmaceutical Active Ingredient (API): Core component in the formulation of antimalarial combination therapies, particularly with dihydroartemisinin.
• Antimalarial Drug Development: Key intermediate or reference standard in R&D for new treatments targeting multidrug-resistant malaria.
• Parasitology Research: Used in *in vitro* and *in vivo* studies to investigate mechanisms of action and resistance in malaria parasites.
• Reference Standard: Serves as a high-purity analytical standard for quality control and regulatory testing in pharmaceutical laboratories.
• Veterinary Pharmaceuticals: Potential application in veterinary medicine for protozoal infections.

Basic Information

Product Name	Tripiperaquine
CAS No.	53658-96-1
Molecular Formula	C₃₀H₃₂Cl₂N₆
Molecular Weight	523.52 g/mol
Synonyms	1,3-Bis[4-(7-chloro-4-quinolyl)-1-piperazinyl]propane; 1,3-Bis(4-(7-chloroquinolin-4-yl)piperazin-1-yl)propane; TPP; Tripiperaquine phosphate; M 1020; Antimalarial agent M1020; RP 22050
EINECS	Contact for details

Quality Control

Our Tripiperaquine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for pharmaceutical applications. Each lot undergoes comprehensive analytical testing, including identification, assay, and impurity profiling via HPLC and other pharmacopeial methods. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to support your regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.5%
Related Substances (HPLC)	Total impurities ≤ 1.5% Any single impurity ≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.