Description

3-Amino-5-Chloropyridine-2-Carboxylic Acid is a high-value, multifunctional heterocyclic building block essential for advanced organic synthesis. Its unique structure, featuring both an amino and a carboxylic acid group on a chlorinated pyridine ring, makes it a critical intermediate for constructing complex molecules with targeted biological activity. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly for kinase inhibitors, anti-infectives, and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging its halogenated pyridine core.
• Ligand and Chelating Agent Precursor: Serves as a starting material for creating specialized ligands used in catalysis and metal complexation studies.
• Material Science Research: Employed in the development of advanced organic materials, such as dyes, pigments, and functional polymers.
• Chemical Biology Probes: Utilized to build molecular probes for studying biological pathways and enzyme functions.
• Custom Synthesis and Contract Manufacturing: A vital building block for custom synthesis houses serving the life sciences sector.

Basic Information

Product Name	3-Amino-5-Chloropyridine-2-Carboxylic Acid
CAS No.	53636-68-3
Molecular Formula	C6H5ClN2O2
Molecular Weight	172.57 g/mol
Synonyms	5-Chloro-3-aminopicolinic Acid; 2-Carboxy-5-chloro-3-aminopyridine; 3-Amino-5-chloropicolinic Acid; 5-Chloro-3-aminopyridine-2-carboxylic Acid; 3-Amino-5-chloro-2-pyridinecarboxylic Acid; 2-Pyridinecarboxylic acid, 3-amino-5-chloro-; 3-Amino-5-chloro-2-carboxypyridine
EINECS	Contact for details

Quality Control

Every batch of 3-Amino-5-Chloropyridine-2-Carboxylic Acid is manufactured under a strict quality management system and undergoes comprehensive analytical testing. We provide full traceability and Certificates of Analysis (COA) confirming identity, purity, and impurity profiles to ensure it meets the exacting standards required for research and commercial synthesis. Our quality commitment supports compliance in cGMP and ISO environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area%)	≥ 99.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.