Description

2-Cyano-3-Mercaptopyridine is a versatile heterocyclic building block featuring both cyano and thiol functional groups, making it a key intermediate for the synthesis of complex molecules. Its unique bifunctional reactivity allows for selective modifications, which is critical for developing advanced pharmaceutical compounds and functional materials. This high-purity intermediate is essential for research and production in the pharmaceutical, agrochemical, and specialty chemical industries seeking to innovate within nitrogen-containing heterocycle chemistry.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system and anti-infective agents.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its heterocyclic core for biological activity.
• Ligand and Catalyst Preparation: Serves as a starting material for creating specialized ligands in coordination chemistry and catalysts for organic transformations.
• Material Science Research: Employed in the development of organic electronic materials, dyes, and polymers due to its electron-withdrawing cyano group and modifiable thiol.
• Bioconjugation and Probe Development: The reactive thiol group makes it suitable for creating biochemical probes, fluorescent markers, and protein conjugation linkers.
• Custom Synthesis and R&D: A valuable scaffold for medicinal chemistry and process research & development in contract research organizations (CROs) and fine chemical companies.

Basic Information

Product Name	2-Cyano-3-Mercaptopyridine
CAS No.	53636-41-2
Molecular Formula	C6H4N2S
Molecular Weight	136.17 g/mol
Synonyms	3-Mercapto-2-cyanopyridine; 2-Pyridinecarbonitrile, 3-mercapto-; 3-Sulfanylpyridine-2-carbonitrile; 3-Mercaptopicolinonitrile; 2-Cyano-3-pyridinethiol; 3-Pyridinethiol, 2-cyano-; 3-Hydroxy-2-cyanopyridine (tautomer); Picolinonitrile, 3-mercapto-
EINECS	Contact for details

Quality Control

Our 2-Cyano-3-Mercaptopyridine is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals, to ensure it meets the high standards required for advanced synthetic applications. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store the product under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.