Description

(3R,5S,5'Ar)-5-(3-Furyl)-3',4,5,5',5'Aα,7',8',8'Aα-Octahydro-7'α-Methylspiro[Furan-3(2H),6'-[6H]Naphtho[1,8-Bc]Furan]-2,2'(4'H)-Dione is a complex spirocyclic furanone derivative with a defined stereochemistry. This compound serves as a valuable chiral building block and synthetic intermediate for advanced organic synthesis, particularly in the development of pharmaceuticals and bioactive molecules. It is primarily needed by research institutions and pharmaceutical R&D departments engaged in the synthesis of novel therapeutic agents and fine chemicals.

Application

• Pharmaceutical Intermediate: Key chiral precursor in the synthesis of potential active pharmaceutical ingredients (APIs) with complex stereochemical requirements.
• Organic Synthesis Building Block: Utilized in advanced organic reactions, including cycloadditions and cross-couplings, to construct intricate polycyclic frameworks.
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies in drug discovery programs.
• Asymmetric Catalysis Studies: Used as a substrate or ligand precursor in the development of new asymmetric synthetic methodologies.
• Fine Chemical Production: Intermediate in the manufacture of specialty chemicals, flavors, and fragrances requiring high stereochemical purity.

Basic Information

Product Name	(3R,5S,5'Ar)-5-(3-Furyl)-3',4,5,5',5'Aα,7',8',8'Aα-Octahydro-7'α-Methylspiro[Furan-3(2H),6'-[6H]Naphtho[1,8-Bc]Furan]-2,2'(4'H)-Dione
CAS No.	53625-15-3
Molecular Formula	C20H22O5
Molecular Weight	342.39 g/mol
Synonyms	7'α-Methylspiro[Furan-3(2H),6'-[6H]Naphtho[1,8-Bc]Furan]-2,2'(4'H)-Dione, 5-(3-Furyl)-3',4,5,5',5'Aα,7',8',8'Aα-Octahydro-, (3R,5S,5'Ar)-; Spiro[naphtho[1,8-bc]furan-6(6H),3'-furan]-2,2'(4'H)-dione derivative; CAS 53625-15-3; (3R,5S,5'aR)-5-(Furan-3-yl)-3',4,5,5',5'a,7',8',8'a-octahydro-7'a-methylspiro[furan-3(2H),6'-[6H]naphtho[1,8-bc]furan]-2,2'(4'H)-dione
EINECS	Contact for details

Quality Control

Our (3R,5S,5'Ar)-5-(3-Furyl)-3',4,5,5',5'Aα,7',8',8'Aα-Octahydro-7'α-Methylspiro[Furan-3(2H),6'-[6H]Naphtho[1,8-Bc]Furan]-2,2'(4'H)-Dione is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis, to ensure consistent identity, purity, and stereochemical integrity. Certificates of Analysis (COA) detailing specifications such as assay, enantiomeric excess, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Maximum Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.