Description

Estra-1,3,5(10)-Trien-17-Ol, 2,3-(Methylenebis(Oxy))-, (17Beta)- is a high-purity steroid derivative, specifically a 2,3-methylenedioxy-protected estradiol analog. This compound is valued for its role as a critical pharmaceutical intermediate and a versatile building block in advanced organic synthesis. It is primarily required by research institutions and manufacturers in the pharmaceutical and biotechnology sectors for the development of novel therapeutic agents and for conducting biochemical research.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of more complex steroid-based drugs and active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a reference standard or a starting material in studies investigating estrogen receptor activity, hormone metabolism, and signal transduction pathways.
• Organic Synthesis: Acts as a protected synthon for the efficient construction of novel chemical entities, leveraging the 2,3-methylenedioxy group for selective reactions.
• Academic & Industrial R&D: Employed in discovery chemistry programs focused on endocrinology, oncology, and metabolic disease research.

Basic Information

Item	Details
Product Name	Estra-1,3,5(10)-Trien-17-Ol, 2,3-(Methylenebis(Oxy))-, (17Beta)-
CAS No.	53586-37-1
Molecular Formula	C19H24O3
Molecular Weight	300.39 g/mol
Synonyms	2,3-Methylenedioxyestradiol; 2,3-Methylenedioxy-17β-estradiol; 17β-Estradiol 2,3-methylenedioxy ether; 2,3-(Methylenebis(oxy))estra-1,3,5(10)-trien-17β-ol; MD-17β-E2; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our Estra-1,3,5(10)-Trien-17-Ol, 2,3-(Methylenebis(Oxy))-, (17Beta)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing specifications such as assay (HPLC), related substances, and physical characteristics are provided to guarantee the material meets your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.