Description

Methyl (S)-(+)-3-Hydroxybutyrate is a high-purity chiral ester, a key building block in asymmetric synthesis and pharmaceutical manufacturing. This compound is valued for its role as a versatile intermediate in the production of fine chemicals, active pharmaceutical ingredients (APIs), and complex natural products. It is essential for research and production in the pharmaceutical, agrochemical, and specialty chemical industries where precise stereochemistry is critical.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the synthesis of β-blockers, statins, and other enantiomerically pure drugs.
• Asymmetric Synthesis: Used as a chiral auxiliary or building block in stereoselective reactions to construct complex molecular architectures.
• Flavor & Fragrance Industry: Serves as a precursor for the production of specific flavoring agents and aroma chemicals.
• Agrochemicals: Employed in the research and development of chiral pesticides and herbicides.
• Biochemical Research: Used in studies related to ketone bodies, metabolism, and enzymatic processes.
• Polymer Chemistry: Acts as a monomer or co-monomer for synthesizing specialized biodegradable polyesters.

Basic Information

Product Name	Methyl (S)-(+)-3-Hydroxybutyrate
CAS No.	53562-86-0
Molecular Formula	C5H10O3
Molecular Weight	118.13 g/mol
Synonyms	(S)-(+)-3-Hydroxybutyric Acid Methyl Ester; Methyl (S)-3-Hydroxybutyrate; (S)-Methyl 3-Hydroxybutanoate; (S)-(+)-Methyl 3-Hydroxybutyrate; (S)-3-Hydroxybutyric Acid Methyl Ester; (S)-MHB; (S)-HBM; L-Methyl 3-hydroxybutyrate
EINECS	Contact for details

Quality Control

Our Methyl (S)-(+)-3-Hydroxybutyrate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for pharmaceutical and fine chemical applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Assay (GC/HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Specific Rotation [α]	+22° to +24° (c=1 in CHCl3)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.