Description

3,3'-Dioctadecylthiacarbocyanine Perchlorate is a lipophilic, cationic cyanine dye salt widely used as a fluorescent membrane probe. Its core value lies in its ability to selectively stain and track cellular membranes, particularly in live-cell imaging and biophysical studies of membrane potential and dynamics. This product is essential for researchers and manufacturers in the fields of cell biology, neuroscience, and diagnostic assay development, where high-purity, photostable fluorescent markers are required.

Application

• Live-Cell Membrane Staining: Visualization of plasma and organelle membranes in fluorescence microscopy.
• Membrane Potential Sensing: Used as a potentiometric dye to monitor changes in mitochondrial and plasma membrane potential.
• Lipid Bilayer and Vesicle Labeling: Incorporation into liposomes and artificial membranes for biophysical research.
• Flow Cytometry: Fluorescent labeling of cells for analysis based on membrane properties.
• Neuronal Activity Imaging: Tracking of neuronal membrane dynamics in electrophysiology and neurobiology studies.
• Diagnostic Kit Component: Potential use as a fluorescent tag in specialized in-vitro diagnostic (IVD) assays.

Basic Information

Product Name	3,3'-Dioctadecylthiacarbocyanine Perchlorate
CAS No.	53533-50-9
Molecular Formula	C53H85ClN2O4S
Molecular Weight	889.80 g/mol
Synonyms	DiOC18(3); DiIC18(3) Perchlorate; 3,3'-Di-Octadecylthiacarbocyanine Perchlorate; 1,1'-Dioctadecyl-3,3,3',3'-tetramethylindocarbocyanine Perchlorate (related analog); Dioctadecyloxacarbocyanine Perchlorate (structural variant); Fluorescent Membrane Probe DiOC18(3); Lipophilic Cationic Dye; Potential-Sensitive Dye DiI; DiIC18(3) (common abbreviation)
EINECS	Contact for details

Quality Control

Our 3,3'-Dioctadecylthiacarbocyanine Perchlorate is produced and tested to meet the stringent requirements of research and diagnostic applications. Each batch undergoes rigorous analytical control, including HPLC for purity verification and spectroscopic methods to confirm identity and performance. A comprehensive Certificate of Analysis (COA) detailing purity, absorbance/fluorescence profiles, and other critical parameters is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccant for long-term stability. The product is strictly light-sensitive (protect from all light exposure) and hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	Dark green to blue-black solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 95.0% (Area %)
Absorption Max (λmax)	550 - 556 nm (in methanol)
Emission Max (λem)	565 - 570 nm (in methanol)
Loss on Drying	≤ 2.0 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.