Description

Succinimido (1,5-Naphthyridin-3-Yl)Formate CAS NO 53512-20-2 is a specialized heterocyclic building block featuring a reactive succinimidyl ester group. This compound is highly valued for its role as a key intermediate in the synthesis of complex molecules, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the life sciences sector for creating novel active pharmaceutical ingredients (APIs) and advanced materials.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, particularly those targeting specific enzyme pathways.
• Bioconjugation Reagent: Used to modify proteins, peptides, or antibodies by reacting with primary amine groups, facilitating the creation of drug conjugates or diagnostic probes.
• Organic Synthesis: Serves as a versatile precursor in constructing complex naphthyridine-containing heterocycles for material science and agrochemical research.
• Proteomics Research: Employed in chemical proteomics for labeling and studying protein function and interactions.
• Chemical Biology Tool: Utilized to develop activity-based probes for investigating biological processes at the molecular level.
• Linker Chemistry: Acts as a key component in the development of cleavable or stable linkers for targeted drug delivery systems.

Basic Information

Product Name	Succinimido (1,5-Naphthyridin-3-Yl)Formate
CAS No.	53512-20-2
Molecular Formula	C13H9N3O3
Molecular Weight	255.23 g/mol
Synonyms	3-(1,5-Naphthyridin-3-yloxycarbonyloxy)-2,5-pyrrolidinedione; 1,5-Naphthyridin-3-yl N-succinimidyl carbonate; N-Succinimidyl (1,5-naphthyridin-3-yl) carbonate; Succinimidyl (1,5-naphthyridin-3-yl) carbonate; NSC 339586; 2,5-Dioxopyrrolidin-1-yl (1,5-naphthyridin-3-yl) carbonate
EINECS	Contact for details

Quality Control

Our Succinimido (1,5-Naphthyridin-3-Yl)Formate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.