Description

Hydroxy-Diphenyl-Acetic Acid 8-Methyl-8-Aza-Bicyclo[3.2.1]Oct-3-Yl Ester (Wxg03166) is a complex organic ester with a fused bicyclic amine structure, serving as a key advanced pharmaceutical intermediate. This compound matters for its role in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting the central nervous system, due to its specific stereochemistry and functional groups. It is primarily needed by research institutions, pharmaceutical development laboratories, and fine chemical manufacturers engaged in the production of specialized therapeutics and novel drug candidates.

Application

• Pharmaceutical Intermediate: Critical building block in the synthesis of tropane alkaloid-derived active pharmaceutical ingredients (APIs).
• Neurological Research: Used in the development and study of compounds targeting cholinergic and other neurotransmitter systems.
• Process Chemistry: Serves as a chiral precursor in multi-step organic synthesis for complex molecule manufacturing.
• Analytical Reference Standard: Employed as a high-purity standard for quality control and method development in analytical laboratories.
• Medicinal Chemistry: Utilized in structure-activity relationship (SAR) studies and lead optimization programs.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Item	Detail
Product Name	Hydroxy-Diphenyl-Acetic Acid 8-Methyl-8-Aza-Bicyclo[3.2.1]Oct-3-Yl Ester (Wxg03166)
CAS No.	53484-68-7
Molecular Formula	C23H27NO3
Molecular Weight	365.47 g/mol
Synonyms	8-Methyl-8-azabicyclo[3.2.1]oct-3-yl 2-hydroxy-2,2-diphenylacetate; Tropine 2-hydroxy-2,2-diphenylacetate; 3-Tropanyl α-Hydroxydiphenylacetate; Diphenylglycolic Acid Tropine Ester; WXG03166; NSC 403169; 8-Azabicyclo[3.2.1]octane-3-carboxylic acid, 8-methyl-, 2-hydroxy-2,2-diphenylethyl ester
EINECS	Contact for details

Quality Control

Our Hydroxy-Diphenyl-Acetic Acid 8-Methyl-8-Aza-Bicyclo[3.2.1]Oct-3-Yl Ester is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing including HPLC for purity, chiral analysis, and identity confirmation to ensure it meets the stringent requirements for pharmaceutical intermediate use. Certificates of Analysis (COA) with detailed chromatographic data are provided and can be tailored to meet specific client or regulatory standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The product is light-sensitive (store away from light) and may be incompatible with strong bases and organic solvents; keep separate from such materials. For long-term storage, consider under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.